Indications

A-B1 is used to treat various conditions caused by thiamine (Vitamin B1) deficiency, including Beriberi and Wernicke-Korsakoff syndrome, as well as neuritis associated with pregnancy and pellagra. It can also be used as a preventive measure in cases of low dietary intake, poor absorption (such as with alcohol use), or increased thiamine needs (such as during pregnancy or a carbohydrate-rich diet).

Pharmacology

Thiamine Hydrochloride (Vitamin B1) is a crucial component for the metabolism of carbohydrates and amino acids. A deficiency in thiamine can lead to an accumulation of pyruvic and lactic acid in tissues, which causes Beriberi. About 1 mg of thiamine is degraded by the body's tissues daily, which is the approximate minimum daily requirement. Thiamine is well-absorbed through the digestive system and distributed throughout the body. Any excess thiamine is excreted in the urine.

Dosage & Administration

• For mild, chronic thiamine deficiency: Doses of up to 30 mg daily, in single or divided doses, are recommended.
• For severe thiamine deficiency: Doses of up to 300 mg daily have been administered.

Interaction

A-B1 has no known severe interactions with other drugs.

Contraindications

This medication is contraindicated in individuals with a hypersensitivity to thiamine.

Side Effects

When administered orally, A-B1 does not typically cause any negative effects, even in doses much higher than the therapeutic dose.

Pregnancy & Lactation

This drug is considered safe for use in neonates, children, pregnant and lactating women, and elderly patients.

Precautions & Warnings

While a severe allergic reaction to this vitamin is rare, you should seek immediate medical attention if you experience symptoms like a rash, itching or swelling (especially of the face, tongue, or throat), severe dizziness, or trouble breathing.

Overdose Effects

Taking an overdose of A-B1 is not expected to cause toxicity.

Therapeutic Class

This medication belongs to the therapeutic class of Vitamin-B preparations.

Storage Conditions

Store this product below 30°C, away from light and moisture. Keep it out of the reach of children.