Indications

Atofix ointment 3% is used topically to treat atopic dermatitis, commonly known as eczema. রেজিস্টার্ড চিকিৎসকের পরামর্শ মোতাবেক ঔষধ সেবন করুন

Composition

0.3% Ointment: Each gram of ointment contains Difamilast INN 3 mg. 1% Ointment: Each gram of ointment contains Difamilast INN 10 mg.

Pharmacology

Difamilast is a phosphodiesterase 4, PDE4, inhibitor. It increases cyclic adenosine 3',5'-monophosphate, cAMP, concentration and consequently suppresses the production of inflammatory cytokines, exerting effects in treatment of atopic dermatitis.

Dosage and Administration

Adult Dosage: An appropriate amount of the Difamilast 1% ointment applied to the affected area twice daily. Pediatric Dosage: An appropriate amount of the Difamilast 0.3% ointment applied to the affected area twice daily. রেজিস্টার্ড চিকিৎসকের পরামর্শ মোতাবেক ঔষধ সেবন করুন

Contraindications

Difamilast is contraindicated in individuals with a known hypersensitivity to the drug.

Side Effects

Well tolerated in recommended dosage. At higher dosage it may cause mild skin reactions at the site of application, such as redness, burning, or stinging.

Pregnancy and Lactation

Difamilast is not recommended for pregnant women or women who may possibly be pregnant. For breastfeeding, safety profile has not been fully established.

Precautions and Warnings

External Use: Atofix ointment is not for oral, ophthalmic, or intravaginal use. Hypersensitivity: If there is any hypersensitivity issue with the use of Atofix, treatment should be discontinued.

Storage Conditions

Keep below 30 degree Celsius temperature, away from light and moisture. Keep out of the reach of children.