Carbizol 10

Presentation: Each tablet contains carbimazole 10 mg.

Indications:Carbizol is indicated in the management of hyperthyroidism, thyrotoxicosis (including thyroid storm), and also for the preparation of patients for thyroidectomy. Carbizol can also be used in combination with radioactiveiodine ablative therapy.

Dosage and Administration: The initial dose for adults is usually 20-60 mg daily, administered in 2-3 divided doses, until the patient is euthyroid. The daily dosage should be divided. The maintenance dose is gradually reduced to maintain a euthyroid state, typically in the range of 5-15 mg per day, which may be taken as a single daily dose. For neonates and children below 12 years, the usual initial dose is 250 mcg/kg/day in divided doses. The usual duration of treatment is 18 to 24 months.

Side Effects: Side effects may include rash, pruritus, skin pigmentation, paraesthesias, urticaria, headache, arthralgia, and gastrointestinal disturbances (including nausea, vomiting, and gastric discomfort), and abnormal hair loss. Less commonly, drug fever, a lupus-like syndrome, vasculitis and nephritis, and hepatic disorders (most commonly jaundice) and taste disturbanceshave been reported.

Precautions:Carbizol should be given with the utmost caution, or not at all, if there is any degree of tracheal obstruction, as high dosages may produce thyroid enlargement and obstructive symptoms may become marked.Caution should also be taken in patients with mild to moderate hepatic impairment.

Carbimazole may cross the placenta and is excreted into breast milk, potentially causing fetal or neonatal hypothyroidism and goitre. The smallest effective dose should be used during pregnancy.

Storage: Keep below 30°C temperature, away from light and moisture. Keep out of the reach of children.

Important Note: This information is for general knowledge and informational purposes only, and does not substitute professional medical advice. Always consult your doctor or pharmacist for specific instructions and guidance regarding your medication. They can assess your individual medical condition and provide the most appropriate advice.