Clob 10

Presentation: Each tablet contains Clobazam 10 mg.

Indications: Clob is indicated for the treatment of:

• Severe anxiety for a short period.
• Epilepsy (as adjunctive therapy in patients not adequately stabilized with anticonvulsant monotherapy).
• Anxiety associated with depression (in combination with sufficient concurrent therapy). 
• Psychovegetative and psychosomatic disorders.  

Dosage and Administration: The dosage is individualized and determined by the physician.

• Anxiety: Adults and adolescents over 15 years: Initial dose is usually 20 mg daily, not exceeding 30 mg daily. Elderly: Maintenance dose of 10-15 mg daily may be sufficient. Children (3-15 years): 5-10 mg daily is often sufficient.
• Epilepsy: Adults and adolescents over 15 years: Start with 5-15 mg daily, gradually increase to a maximum of about 80 mg daily. Children: Start with 5 mg daily, maintenance dose is usually 0.3-1.0 mg/kg daily.

Administer orally, with or without food. Tablets can be swallowed whole or crushed and mixed with applesauce. It is generally recommended to take the largest portion of the daily dose in the evening. Treatment duration should be as short as possible, not exceeding 8-12 weeks including tapering off.

Side Effects: Very common side effect is somnolence, especially at the beginning of treatment. Common side effects include sedation, dizziness, disturbance in attention, slow or disordered speech, headache, tremor, dry mouth, nausea, and constipation. Less common side effects may include confusion, irritability, aggression, depression, memory impairment, and muscle weakness.

Precautions: Use with caution in elderly patients due to increased risk of adverse reactions. May cause drowsiness and dizziness; caution when driving or operating machinery. Avoid alcohol. Use with caution in patients with respiratory insufficiency, hepatic or renal impairment, and a history of drug dependence. May increase the risk of suicidal thoughts. Inform the physician if pregnant or breastfeeding. Do not stop taking Clob abruptly due to the risk of withdrawal symptoms.

Storage: Store below 30°C in a dry place, protected from light. Keep out of reach of children.

Important Note: This information is for general knowledge and informational purposes only, and does not substitute professional medical advice. Always consult your doctor or pharmacist for specific instructions and guidance regarding your medication. They can assess your individual medical condition and provide the most appropriate advice.