Dactus 1 

Presentation: Dactus 1 Tablet contains Glimepiride BP 1 mg as the active pharmaceutical ingredient. It is presented as a tablet for oral administration and is usually available in blister packs.

Indications: Dactus is indicated as an adjunct to diet and exercise to lower blood glucose in adults with type 2 diabetes mellitus when hyperglycemia cannot be controlled by diet and exercise alone. It may be used with metformin when diet, exercise, and either Dactus or metformin alone do not provide adequate glycemic control. Dactus is also indicated for use in combination with insulin to lower blood glucose in patients whose hyperglycemia cannot be controlled by diet and exercisealong with an oral hypoglycemic agent.  

Dosage and Administration: The usual starting dose is 1-2 mg once daily, administered with breakfast or the first main meal. The maximum starting dose should not exceed 2 mg. The usual maintenance dose is 1 to 4 mg daily, with a maximum recommended dose of 8 mg once daily. Dosage increases, after reaching 2 mg, should be made in increments of not more than 2 mg at 1-2 week intervals based on blood glucose response. The timing and distribution of doses are determined by the physician, considering the patient's lifestyle.

Side Effects: The most common side effect is hypoglycemia (low blood sugar), with symptoms potentially including sweating, tremor, anxiety, confusion, dizziness, and palpitations. Other possible side effects may include temporary visual impairment, nausea, vomiting, diarrhea, abdominal pain, and skin reactions like urticaria.

Precautions: Dactus is contraindicated in patients with known hypersensitivity to glimepiride, other sulfonylureas, other sulfonamides, or any excipients, as well as in diabetic ketoacidosis with or without coma, severe renal impairment, and severe hepatic dysfunction. It is generally not recommended during pregnancy or breastfeeding. Caution should be exercised in patients with impaired renal or hepatic function and in elderly or debilitated individuals who may be more prone to hypoglycemia. Alcohol consumption should be avoided or minimized.

Storage: Store Dactus 1 tablets below 30°C. Keep away from light and out of the reach of children.

Important Note: This information is for general knowledge and informational purposes only, and does not substitute professional medical advice. Always consult your doctor or pharmacist for specific instructions and guidance regarding your medication. They can assess your individual medical condition and provide the most appropriate advice.