Deflacort 30 

Presentation: Deflacort 30 is presented as tablets, each containing 30mg of deflazacort.

Indications: Deflacort (deflazacort) is a corticosteroid indicated for the treatment of various inflammatory and autoimmune conditions, including:

• Allergic disorders (e.g., severe asthma, anaphylaxis).
• Rheumatoid arthritis and other rheumatic diseases.
• Systemic lupus erythematosus (SLE) and other connective tissue disorders.
• Skin conditions (e.g., pemphigus, bullous pemphigoid).
• Kidney disorders (e.g., nephrotic syndrome).
• Inflammatory bowel disease (e.g., ulcerative colitis, Crohn's disease).
• Eye inflammation (e.g., uveitis, optic neuritis).
• Blood disorders (e.g., autoimmune hemolytic anemia, idiopathic thrombocytopenic purpura).
• Certain cancers (palliative management of leukemia, lymphoma, myeloma).
• Prevention of organ rejection after transplantation.
• Duchenne Muscular Dystrophy (DMD) in patients 5 years of age and older.

Dosage and Administration: The dosage of Deflacort 30 is highly variable and depends on the specific condition being treated, its severity, and the patient's response. Always follow your doctor's precise instructions.

• Adults: The initial dose may range from 6 to 90 mg per day, depending on the condition. Maintenance doses are often lower and are adjusted based on clinical response.
• Children: Dosage is usually based on body weight and the severity of the condition, typically ranging from 0.25 to 1.5 mg/kg per day. For Duchenne Muscular Dystrophy in patients ≥ 5 years, the dose is 0.9 mg/kg/day once orally.
• Deflacort tablets are taken orally. The daily dose is usually administered as a single dose in the morning.
• Do not stop taking this medication suddenly, especially after long-term use, as it can lead to withdrawal symptoms. The dosage should be gradually reduced under medical supervision.

Side Effects: Common side effects of deflazacort are similar to other corticosteroids and may include:

• Increased appetite and weight gain.
• Fluid retention (swelling).
• Mood changes, irritability, and difficulty sleeping.
• Increased blood pressure.
• Acne.
• Increased hair growth.
• Thinning skin and easy bruising.
• Impaired wound healing.
• Increased risk of infections.
• Osteoporosis (bone thinning).
• Muscle weakness.
• Cataracts and glaucoma.
• Increased blood sugar (hyperglycemia) or development of diabetes.

Deflazacort may have a slightly lower risk of some side effects, such as bone loss, compared to other corticosteroids, but this can vary between individuals.

Precautions: Deflacort (deflazacort) is contraindicated in patients with systemic fungal infections and known hypersensitivity to deflazacort or any of its components. Use with caution in patients with:

• Diabetes mellitus.
• Hypertension or heart failure.
• Peptic ulcer disease or other gastrointestinal disorders.
• Osteoporosis or increased risk of fractures.
• Psychiatric disorders.
• Active infections (may mask signs of infection or worsen existing infections).
• Glaucoma.
• Liver or kidney disease.
• Hypothyroidism.
• Pregnancy or breastfeeding (use only if clearly needed and benefits outweigh risks). Live virus vaccines should generally not be given to patients receiving corticosteroids.

Storage: Store Deflacort 30 tablets below 30°C in a dry place, protected from light and moisture. Keep out of reach of children.

Important Note: This information is for general knowledge and informational purposes only, and does not substitute professional medical advice. Always consult your doctor or pharmacist for specific instructions and guidance regarding your medication. They can assess your individual medical condition and provide the most appropriate advice.