Diatrol MR 60 

Presentation:Diatrol MR 60 is a modified-release tablet containing Gliclazide 60 mg as the active pharmaceutical ingredient.It is usually available in blister packs. The modified-release formulation allows for a once-daily dosage.  

Indications:Diatrol MR 60 is indicated for the treatment of type 2 diabetes mellitus in adults when diet, exercise, and weight reduction alone have not been adequate in controlling blood glucose levels.Gliclazide is a sulfonylurea that works by increasing the release of insulin from the beta cells of the pancreas and by reducing glucose production in the liver.The modified-release formulation provides a sustained release of gliclazide, allowing for once-daily administration.  

Dosage and Administration: The dosage of Diatrol MR 60 should be determined by the physician based on the individual patient's blood glucose levels. The usual starting dose is 30 mg once daily, but some patients may start at 60 mg once daily. Dosage adjustments are typically made in increments of 30 mg, usually at intervals of at least 2 weeks, based on the patient's glycemic response. The maximum recommended daily dose is 120 mg once daily.Diatrol MR 60 should be taken orally once daily at breakfast time. The tablet should be swallowed whole and not crushed or chewed.Maintaining regular meal times is important while taking this medication.

Side Effects:The most common side effect of Diatrol MR 60 is hypoglycemia (low blood sugar), which can occur if meals are skipped, during strenuous exercise, or when used in combination with other antidiabetic agents.Symptoms of hypoglycemia may include sweating, tremor, anxiety, confusion, dizziness, and palpitations.Other potential side effects include gastrointestinal disturbances such as nausea, vomiting, diarrhea, and abdominal pain.Skin reactions like rash, itching, and hives may occur.Rarely, liver function abnormalities and blood disorders have been reported. Weight gain may also occur with sulfonylureas.  

Precautions:Diatrol MR 60 is contraindicated in patients with type 1 diabetes mellitus, diabetic ketoacidosis, severe renal or hepatic impairment, and known hypersensitivity to gliclazide or other sulfonylureas.It should be used with caution in elderly patients, those with malnutrition, and those with adrenal or pituitary insufficiency, as they may be at higher risk of hypoglycemia. Alcohol consumption should be avoided or minimized as it can affect blood glucose levels.Certain medications can interact with gliclazide, potentially altering its blood glucose-lowering effect.Inform your doctor about all other medications you are taking. Regular blood glucose monitoring is necessary during treatment.

Storage:Store Diatrol MR 60 tablets below 30°C in a dry place, protected from light.Keep out of the reach of children. Do not use after the expiry date stated on the packaging.

Important Note: This information is for general knowledge and informational purposes only, and does not substitute professional medical advice. Always consult your doctor or pharmacist for specific instructions and guidance regarding your medication. They can assess your individual medical condition and provide the most appropriate advice.