Emazid M 500     

Presentation:Emazid M 500 tablets are film-coated and contain 5 mg of empagliflozin and 500 mg of metformin hydrochloride.

Indications: Emazid M is indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus when treatment with both empagliflozin and metforminis appropriate. This includes patients:  

• Insufficiently controlled on their maximally tolerated dose of metformin alone.  
• In combination with other medicinal products for the treatment of diabetes, in patients insufficiently controlledwith metformin and these medicinal products.  
• Already being treated with the combination of empagliflozin and metformin as separate tablets. Empagliflozin, a component of Emazid M 500, is also indicated to reduce the risk of cardiovascular death in adults with type 2 diabetes mellitus and established cardiovasculardisease.  

Dosage and Administration: The dosage should be individualized based on effectiveness and tolerability, not exceeding the maximum recommended daily dose of metformin hydrochloride (2000 mg) and empagliflozin (25 mg). Emazid M 500 is usually taken twice daily with meals to reduce gastrointestinal side effects associated with metformin.Your doctor will determine the appropriate dose for you. Renal function should be assessed before initiating Emazid M 500 and periodically thereafter. Emazid M 500 is contraindicated in patients with an eGFR below 45 mL/min/1.73 m².  

Side Effects:Common side effects may include urinary tract infection, female genital mycotic infections, nausea, vomiting, diarrhea, abdominal pain, and increased urination.Hypoglycemia may occur when Emazid M 500 is used in combination with insulin or insulin secretagogues.

Precautions:Emazid M 500 is contraindicated in patients with severe renal impairment (eGFR < 45 mL/min/1.73 m²), acute or chronic metabolic acidosis including diabetic ketoacidosis, or a history of serious hypersensitivity reaction to empagliflozin, metformin hydrochloride, or any of the excipients.It is not recommended for use in patients with type 1 diabetes. Assess renal function before initiation and monitor periodically. Avoid excessive alcohol intake. Temporary discontinuation may be needed for surgery or iodinated contrast imaging. Counsel patients about the potential risk of lactic acidosis and diabetic ketoacidosis. It is unsafe to consume Emazid M 500 with alcohol and it is not recommended for use during pregnancy or breastfeeding.  

Storage:Store below 30°C temperature, protected from light & moisture.Keep out of the reach of children.

Important Note: This information is for general knowledge and informational purposes only, and does not substitute professional medical advice. Always consult your doctor or pharmacist for specific instructions and guidance regarding your medication. They can assess your individual medical condition and provide the most appropriate advice. As you are in Bangladesh, always refer to local medical guidelines and consult a healthcare professional registered in Bangladesh for any health concerns or before taking any medication.