Indications

Feglo-FZ (Ferrous Ascorbate, Folic Acid & Zinc) is indicated for the prophylaxis (prevention) of iron deficiency, especially when supplementary zinc and iron are required due to an inadequate diet during pregnancy and anemia.

Pharmacology

This is a combination of three nutritional supplements:

• Ferrous Ascorbate: A combination of iron and Vitamin C. Iron replenishes the body's iron stores to correct iron deficiency anemia. Vitamin C (Ascorbate) is included to enhance the absorption of iron.
• Folic Acid: A B vitamin vital for the formation of red blood cells (which carry oxygen). It is essential in pregnancy for the development of the unborn baby's brain and spinal cord.
• Zinc: A micromineral that provides nutrition.

Dosage & Administration

• Adult & Elderly: One tablet a day before or after a meal (absorption is food-independent), or as directed by the physician.
• Severe Cases: Two tablets a day may be required, as prescribed by the physician.
• Pediatric Patients: Safety and effectiveness have not been established.

Interaction

• Tetracycline Antibiotics: Iron chelates with tetracycline. Feglo-FZ should not be taken within two hours of oral tetracycline antibiotics, as it interferes with their absorption.
• Penicillamine and Antacids: Concurrent administration may impair the absorption of iron.
• Renal Failure: A risk of zinc accumulation may exist in patients with renal failure.

Contraindications

This drug is contraindicated in patients with:

• Haemolytic anaemia.
• Conditions involving increased body iron content.
• Increased hypersensitivity to any of its components.

Side Effects

Side effects are generally mild and transient, and include:

• Epigastric pain
• Nausea, vomiting, diarrhea, constipation
• Heartburn
• Allergic sensitization has been reported following the administration of folic acid.

Pregnancy & Lactation

• Pregnancy: Consult a physician if pregnant or planning to become pregnant. Administration in the first trimester should be avoided unless a definite iron deficiency is observed. Prophylaxis is justified during the remainder of the pregnancy, especially when zinc supplementation is required.
• Lactation: Consult a physician if currently breast-feeding.

Precautions & Warnings

Caution should be exercised in patients who may develop iron overload, such as those with haemochromatosis, haemolytic anemia, or red cell aplasia. Failure to respond to treatment should prompt an investigation for other underlying causes of anemia.

Overdose Effects

The clinical course of acute iron overdosage can be variable. Initial symptoms may include abdominal pain, nausea, vomiting, diarrhoea, tarry stools, hypotension, tachycardia, metabolic acidosis, and can progress to more severe effects such as seizures, shock, and coma.

Therapeutic Class

Iron, Vitamin & Mineral Combined preparation.

Storage Conditions

Keep below 30∘C, away from light and moisture. Keep out of the reach of children.