Jardian 25

Presentation: Each tablet contains 25 mg of empagliflozin.

Indications: Jardian is indicated in adults with type 2 diabetes mellitus:  

• As an adjunct to diet and exercise to improve glycemic control.  
• To reduce the risk of cardiovascular death in adultpatients with type 2 diabetes mellitus and established cardiovascular disease.  

Dosage and Administration:  

• The recommendedstarting dose of Jardian is 10 mg once daily.
• In patients tolerating empagliflozin who require additional glycemic control, the dose can be increased to 25 mg once daily.
• Jardian should be taken orally once daily in the morning, with or without food.
• In patients with volume depletion, correcting this condition prior to initiation of empagliflozin is recommended.
• Renal function should be assessed prior to initiation of Jardian and periodically thereafter. Jardian is not recommended in patients with an eGFR less than 45 mL/min/1.73 m².

Side Effects: The most common side effects associated with Jardian include:

• Urinary tract infections
• Female genital mycotic infections

Other common side effects may include:

• Increased urination
• Thirst
• Nausea
• Hypoglycemia (when used with insulin or sulfonylureas)
• Volume depletion
• Dizziness

Precautions:

• Jardian is contraindicated in patients with a history of serious hypersensitivity reaction to empagliflozin or any of the excipients, severe renal impairment (eGFR < 30 mL/min/1.73 m²), end-stage renal disease, or those on dialysis.
• Use of Jardian is not recommended during the second and third trimesters of pregnancy and during breastfeeding.
• Caution should be exercised when Jardian is used concomitantly with diuretics due to potential for increased diuresis.
• An increased risk of diabetic ketoacidosis has been reported with SGLT2 inhibitors, including empagliflozin. Patients should be educated on the signs and symptoms and risk factors.
• Rare cases of Fournier's gangrene (necrotizing fasciitis of the perineum) have been reported with SGLT2 inhibitors.

Storage: Store below 30°C in a dry place, protected from light and moisture. Keep out of reach of children.

Important Note: This information is for general knowledge and informational purposes only, and does not substitute professional medical advice. Always consult your doctor or pharmacist for specific instructions and guidance regarding your medication. They can assess your individual medical condition and provide the most appropriate advice.