Lyroxen 50 Tablet

Presentation: Lyroxen 50 is available as tablets, each containing Naproxen BP 50 mg. It is a product of Beximco Pharmaceuticals Ltd. in Bangladesh and is usually available in blister packs. The tablets are typically white to off-white, round or oval-shaped.

Indications: Lyroxen (Naproxen) is a non-steroidal anti-inflammatory drug (NSAID) indicated for the relief of:

• Mild to moderate pain such as muscle aches, headaches, toothaches.
• Pain and inflammation associated with musculoskeletal disorders such as osteoarthritis, rheumatoid arthritis, ankylosing spondylitis.
• Acute gout.
• Primary dysmenorrhea (menstrual cramps).

Dosage and Administration: Lyroxen 50 tablets should be swallowed whole with water, preferably with or after food to minimize gastrointestinal irritation. The dosage depends on the condition being treated and the patient's response, as directed by a physician.

• For pain relief: The usual initial dose is 200-400 mg, followed by 200 mg every 6-8 hours as needed, with a maximum daily dose usually not exceeding 1000 mg on the first day and 800 mg on subsequent days.
• For osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis: The usual dose is 250-500 mg twice daily in the morning and evening.
• For acute gout: The usual initial dose is 750 mg, followed by 250 mg every 8 hours until the attack subsides.
• For dysmenorrhea: The usual initial dose is 500 mg, followed by 250 mg every 6-8 hours as needed.

Side Effects: Common side effects of Lyroxen (Naproxen) may include:

• Heartburn
• Stomach pain
• Nausea
• Constipation
• Headache
• Dizziness
• Drowsiness

Less common side effects may include:

• Vomiting
• Diarrhoea
• Indigestion
• Skin rash or itching
• Fluid retention (swelling)
• Tinnitus (ringing in the ears)

Serious side effects are rare but can include gastrointestinal ulcers, bleeding, or perforation, and cardiovascular events.

Precautions: Lyroxen (Naproxen) is contraindicated in patients with known hypersensitivity to naproxen or other NSAIDs, and in patients with a history of asthma, urticaria, or allergic-type reactions after taking aspirin or other NSAIDs.It is also contraindicated in patientswith active peptic ulcer, gastrointestinal bleeding, or severe renal impairment.

Caution should be exercised in patients with a history of peptic ulcer disease, heart disease, hypertension, liver disease, or bleeding disorders. NSAIDs may increase the risk of serious cardiovascular thrombotic events, myocardial infarction, and stroke. Use in the elderly should be with caution.

Use in Pregnancy and Lactation: The use of Lyroxen during pregnancy, especially in the third trimester, should be avoided due to potential risks to the foetus. It is not recommended for use during breastfeeding as naproxen is excreted in breast milk. Consult a healthcare professional before use.

Storage: Store below 30°C in a dry place, protected from light. Keep out of reach of children.

Important Note: This information is for general knowledge and informational purposes only, and does not substitute professional medical advice. Always consult your doctor or pharmacist for specific instructions and guidance regarding your medication. They can assess your individual medical condition and provide the most appropriate advice.