ACME's Milk of Magnesia Plus contains:

• Magnesium Hydroxide BP: 300 mg per 5 ml (This acts as both an antacid and a laxative)
• Liquid Paraffin BP: 1.25 ml per 5 ml (This acts as a lubricant laxative to ease bowel movements)

Therefore, Milk of Magnesia Plus provides a dual action: magnesium hydroxide draws water into the bowel to stimulate movement, while liquid paraffin lubricates the stool for easier passage.

Indications:

• Constipation
• Hyperacidity with constipation
• Anorectal disorders
• Post-operative constipation
• Constipation associated with chronic cholecystitis
• Hernia (to avoid straining)

Dosage and Administration:

• Adults and Children over 12 years: 15 - 30 ml (3 - 6 teaspoonsful) before breakfast or at bedtime.
• Children 7 to 12 years: 7.5 – 15 ml (1.5 – 3 teaspoonsful) at bedtime.  
• Children 3 – 7 years:5 – 10 ml (1 – 2 teaspoonsful) taken at bedtime.  
• The dose may be taken with water or milk if necessary.
• It is important to drink sufficient fluids while taking this medication.
• Do not take for more than 1 week unless under doctor's supervision.

Contraindications:

• Acute gastrointestinal problems such as abdominal pain.
• Renal failure.
• Existing electrolyte imbalance.
• Symptoms of appendicitis.
• Acute surgical abdomen.
• Myocardial disease.
• Not recommended for use in patients with difficulty swallowing or impaired neurodevelopment (due to the liquid paraffin content and risk of aspiration).

Side Effects:

Common side effects may include:

• Irritation in the rectum (with excessive dose)
• Anal irritation and seepage
• Potassium deficiency (thirst, weakness, nausea, and diarrhea)
• Abdominal discomfort, pain, or cramps

Less common side effects associated with liquid paraffin can include foreign-body granulomatous reactions, vasospasm, and lipoid pneumonia (if aspirated).

Precautions and Warnings:

• Use with caution in patients with renal and hepatic dysfunction.
• Maintain sufficient liquid intake.
• May impair the absorption of fat-soluble vitamins and possibly other compounds.
• Consult a doctor before use in pregnant or breastfeeding women.
• Use with caution in children, especially those under 12 years.

Drug Interactions:

Milk of Magnesia (magnesium hydroxide) can decrease the absorption of other drugs, including:

• Tetracycline antibiotics
• Digoxin
• Mycophenolate
• Phosphate supplements
• Certain azole antifungals (ketoconazole, itraconazole)
• Quinolone antibiotics (e.g., ciprofloxacin, levofloxacin)
• Cimetidine, diuretics, famotidine, and ranitidine may induce stomach or intestinal discomfort when taken with Milk of Magnesia Plus.

Storage:

Keep below 30°C and away from light and moisture. Keep out of reach of children.

Note: This information is for general knowledge and informational purposes only and does not substitute professional medical advice. Always consult your doctor or pharmacist for specific instructions and guidance regarding your medication.