Prelin 25 Capsule contains 25 mg of Pregabalin.

Brand Name: Prelin

Generic Name: Pregabalin

Manufacturer: Drug International Ltd. (in Bangladesh)

Presentation: Each capsule contains Pregabalin BP 25 mg. It is usually available in strips. 

Indications: Prelin is indicated for the management of:

• Neuropathic pain associated with diabetic peripheral neuropathy (DPN).
• Postherpetic neuralgia(PHN).  
• Fibromyalgia.
• Neuropathic pain associated with spinal cord injury.
• As adjunctive therapy for the treatment of partial-onset seizures in patients 1 month of age and older. 
• Generalized Anxiety Disorder (GAD).

Dosage and Administration: The dosage is individualized by your doctor. However, some general recommendations:

• The starting dose for neuropathic pain is typically 75 mg per day, given in two or three divided doses. This may be increased gradually to a maximum of 300 mg per day within the first week, based on response and tolerability. Some patients may need up to 600 mg per day.
• For fibromyalgia, the starting dose is 75 mg twice a day (150 mg/day), which may be increased to 150 mg twice a day (300 mg/day) within one week. The recommended dose is 300 to 450 mg/day.
• For partial-onset seizures, the starting dose should not exceed 150 mg/day (75 mg twice daily or 50 mg three times daily). The dose may be increased to a maximum of 600 mg/day.
• Prelin capsules can be taken with or without food. Swallow the capsule whole with water.

Side Effects: The most common side effects include:

• Dizziness
• Sleepiness (somnolence)
• Dry mouth
• Swelling (edema)
• Blurred vision
• Weight gain
• Difficulty with concentration/attention

Less common side effects may include increased appetite, euphoria, confusion, irritability, ataxia (impaired coordination), tremor, and others.

Precautions:

• Use with caution in patients with kidney disease; dose adjustment may be needed.
• Prelin may cause drowsiness and dizziness, so avoid driving or operating machinery until you know how it affects you.
• Inform your doctor if you experience any vision changes.
• Be aware of potential mood changes, new or worsening depression, or suicidal thoughts or behavior.
• Do not stop taking the medication suddenly without talking to your doctor, as withdrawal symptoms may occur. 
• Avoid alcohol, as it may increase drowsiness and dizziness.
• Inform your doctor if you are pregnant, planning to conceive, or breastfeeding.

Contraindications: Prelin is contraindicated in patients with known hypersensitivity to pregabalin or any other components of the product.

Drug Interactions: Prelin may interact with other central nervous system depressants, including opioids and benzodiazepines. Inform your doctor about all medications you are taking.

Storage: Keep in a cool and dry place (below 30°C), protected from light and moisture. Keep out of reach of children.

Important Note: This information is for general knowledge and informational purposes only and does not substitute professional medical advice. Always consult your doctor or pharmacist for specific instructions and guidance regarding your medication. They can assess your individual medical condition and provide the most appropriate advice.