Sinjard 25 

Presentation: Each film-coated tablet of Sinjard 25 contains Empagliflozin INN 25 mg.

Indications: Sinjard is indicated in adults with type 2 diabetes mellitus to improve glycemic control as:  

• Monotherapy: In patients inadequately controlled by diet and exercise alone and forwhom metformin is not appropriate due to intolerance or contraindications.
• Add-on combination therapy: In combination with other glucose-lowering medicinal products including metformin, sulfonylureas, pioglitazone, and insulin. Empagliflozin is also indicated to reduce the risk of cardiovascular death in adults with type 2 diabetes mellitus and established cardiovasculardisease.

Dosage and Administration: The recommended starting dose of Sinjard is 10 mg once daily. In patients tolerating empagliflozin 10 mg once daily who have an eGFR ≥ 60 mL/min/1.73 m² and need additional glycemic control, the dose can be increased to 25 mg once daily. The maximum daily dose is 25 mg. Sinjard can be taken with or without food at any time of the day.

Side Effects: Common side effects may include urinary tract infections, genital mycotic infections, increased urination, thirst, and nausea. Hypoglycemia may occur when used in combination with insulin or sulfonylureas.

Precautions: Sinjard is contraindicated in patients with severe renal impairment (eGFR < 30 mL/min/1.73 m²), end-stage renal disease, or dialysis. It is not recommended for use in patients with moderate renal impairment (eGFR < 60 mL/min/1.73 m²) for glycemic control. Caution should be exercised in patients with a history of urinary tract infections or genital mycotic infections. Assess renal function prior to initiation and periodically thereafter.

Storage: Store below 30°C in a dry place, protected from light and moisture. Keep out of reach of children.

Important Note: This information is for general knowledge and informational purposes only, and does not substitute professional medical advice. Always consult your doctor or pharmacist for specific instructions and guidance regarding your medication. They can assess your individual medical condition and provide the most appropriate advice.