Supraphen, Ophthalmic Solution - (0.50%) contains Chloramphenicol 0.5%.It is manufactured by Gaco Pharmaceuticals Ltd.  

Indications:

Supraphen eye drops are indicated for the treatment of ocular infections involving the conjunctiva and/or cornea caused by susceptible organisms, including:

• Staphylococcus aureus
• Streptococcus pneumoniae
• Escherichia coli
• Haemophilus influenzae
• Klebsiella/Enterobacter spp.
• Moraxella lacunata
• Neisseria species

Pharmacology:

Chloramphenicol is a broad-spectrum bacteriostatic antibiotic. It inhibits bacterial protein synthesis by interfering with the transfer of activated amino acids from soluble RNA to ribosomes. 

Dosage and Administration:

• Adults and Children: Instill 1 or 2 drops in the conjunctival sac 4 to 6 times per day for the first 72 hours, and then every 4 hours thereafter. 
• Treatment should be continued for approximately 7 days but should not exceed 3 weeks without re-evaluation by a physician.

Contraindications:

Supraphen is contraindicated in individuals with a history of hypersensitivity to Chloramphenicol or any other ingredients in the preparation. 

Side Effects:

Systemic adverse reactions are not commonly observed with short-term topical use. The most frequently reported side effects include:

• Burning
• Stinging 
• Conjunctival hyperemia (redness of the eye) 
• Allergic or inflammatory reactions
• Vesicular and maculopapular dermatitis (skin rashes) 

Precautions and Warnings:

• Supraphen ophthalmic solution should never be given for minor infections or for prophylaxis. 
• Repeated courses and prolonged treatment should be avoided. 
• Blood dyscrasias (serious blood disorders) may occur after prolonged ophthalmic use, although this is rare. 
• Avoid touching the dropper tip to any surface, including the eye, to prevent contamination. 
• Do not wear contact lenses until the infection clears up. 

Pregnancy and Lactation:

Safety for use during pregnancy and lactation has not been established. Use only when considered essential by a physician.

Storage Conditions:

Store in a cool place (between 2°C and 8°C) and protect from light. Do not use after 30 days of first opening. Keep out of reach of children.

Note: This information is for general knowledge and informational purposes only and does not substitute professional medical advice. Always consult your doctor or pharmacist for specific instructions and guidance regarding your medication.