💊 T-Cef (Cefixime)

T-Cef is a third-generation cephalosporin antibiotic. It is "bactericidal," meaning it kills a wide range of bacteria by preventing them from building their cell walls. It is highly stable against the enzymes (beta-lactamases) that bacteria often use to resist other antibiotics like penicillin.

📋 Indications

T-Cef is used to treat various acute bacterial infections:

• Upper Respiratory (URTI): Ear infections (otitis media) and throat infections.
• Lower Respiratory: Bronchitis.
• Urinary Tract (UTI): Cystitis and kidney infections (pyelonephritis).
• Other: Typhoid fever.

🥄 Dosage & Administration

Absorption is not affected by food. A typical course is 7 days, but it can be extended to 14 days.

• Adults & Children (>10 years or >50 kg): 200 mg to 400 mg daily, as a single dose or two divided doses.
• Children (6 months to 10 years): 8 mg/kg daily.
  • 6 months–1 year: 3.75 ml daily.
  • 1–4 years: 5 ml daily.
  • 5–10 years: 10 ml daily.
• Typhoid: 5 mg/kg twice daily for 10–14 days.
• Renal Impairment: If creatinine clearance is below 20 ml/min, do not exceed 200 mg per day.

⚠️ Safety & Side Effects

• Common: Diarrhea and stool changes (more common with higher doses), nausea, and abdominal pain.
• Occasional: Headache, dizziness, and mild skin rashes.
• Contraindications: 🛑 Do not use if you have a known allergy to cephalosporins.
• Cross-Allergy: Use with caution if you are allergic to penicillin, as some patients react to both.

🤰 Pregnancy & Lactation

• Pregnancy: Use only if clearly needed and prescribed by a doctor.
• Lactation: It is unknown if Cefixime passes into breast milk; consult your physician before breastfeeding while on this medication.

📦 Storage

• Store below 30°C.
• Protect from light and moisture. Keep out of reach of children. 🚫👶