Ubiden Q 200 

Presentation: Capsules containing Coenzyme Q10 (Ubidecarenone) 200 mg. 

Indications: Indicated for the treatment and prevention of Coenzyme Q10 deficiency and mitochondrial disorders. Also used in various conditions including:

• Infertility: Female (e.g., poor ovarian reserve, polycystic ovary syndrome), male infertility.  
• Neurological disorders:Myopathy, ataxia, genetic neuromuscular disease, migraine,muscular dystrophy, Parkinson's disease, Alzheimer's disease.  
• Cardiovascular disease:Congestive heart failure,high blood pressure, angina, cardiomyopathy, heart protection during surgery.
• Others: Periodontal gum disease, diabetes, exercise performance, cancer, asthma, thyroid disorder.

Dosage and Administration: Dosage varies depending on the condition being treated:

• Co-enzyme Q10 deficiency: 150 mg daily.
• Mitochondrial disorders: 150-160 mg daily or 2 mg/kg/day.
• Heart failure in adults: 100 mg per day divided into 2 or 3 doses.
• Recent myocardial infarction: 120 mg daily in 2 divided doses.
• High blood pressure: 120-200 mg per day divided into 2 doses.
• Isolated systolic hypertension: 60 mg twice daily.
• Preventing migraine headache: 100 mg three times daily.
• Parkinson's disease: 300 mg to 2400 mg per day in 3-4 divided doses.
• Infertility in men: 200-300 mg per day.
• Muscular dystrophy: 100 mg per day.

It is generally recommended to divide the total daily dose and take it with food, especially food with high lipid content, to improve absorption and reduce potential side effects. Always follow the physician's instructions.

Side Effects: Coenzyme Q10 is generally safe for most adults. Mild side effects may include stomach upset, loss of appetite, nausea, vomiting, and diarrhea. Allergic skin rashes can occur in some individuals.

Precautions: Contraindicated in patients with hypersensitivity to Coenzyme Q10 or any excipients and in patients scheduled for surgery in the next two weeks.

Caution should be taken in patients with diabetes or hypoglycemia as Coenzyme Q10 may lower blood sugar levels. Caution is also advised in patients with low blood pressure or those taking blood pressure medications as it may decrease blood pressure.

Coenzyme Q10 may interact with:

• Antihypertensive drugs: May cause blood pressure to go too low.
• Anticancer drugs (Alkylating agents): There is a concern that antioxidants might decrease their effectiveness.
• Warfarin: May decrease the effectiveness of warfarin (Coumadin).
• Statins: May reduce the endogenous synthesis of Coenzyme Q10.
• Beta-blockers: May inhibit some Coenzyme Q10 dependent enzymes.
• Antidiabetic medications: May improve glycemic control, potentially requiring dose adjustment.
• Thyroid drugs: May alter the effect of thyroid drugs.
• Doxorubicin: May help reduce its cardiotoxicity.

Coenzyme Q10 should not be used during pregnancy and breastfeeding.

Storage: Keep in a dry place away from light and heat. Keep out of reach of children.

Important Note: This information is for general knowledge and informational purposes only, and does not substitute professional medical advice. Always consult your doctor or pharmacist for specific instructions and guidance regarding your medication. They can assess your individual medical condition and provide the most appropriate advice.