Udihep 150 

Presentation: Each tablet contains Ursodeoxycholic Acid BP 150 mg. It is usually available in blister packs. The specific manufacturer in Bangladesh may be Mundipharma (BD) Pvt. Ltd.

Indications: Udihep (Ursodeoxycholic Acid) is indicated for:

• Dissolving radiolucent, non-calcified gallstones in patients with a functional gallbladder.
• Treatment of primary biliary cirrhosis (PBC).
• Management of liver disorders associated with cystic fibrosis in children aged 6 years and older.
• May be used for other cholestatic liver diseases.

Dosage and Administration: The dosage depends on the condition being treated and the patient's body weight, as directed by a physician. Udihep tablets are usually taken orally after meals with a glass of water. Do not crush or chew the tablets.

• Dissolution of gallstones: Typically 8-12 mg/kg/day, either as a single nighttime dose or in divided doses. The duration of treatment may be several months.
• Primary biliary cirrhosis: Typically 10-15 mg/kg/day in 2-4 divided doses.
• Cystic fibrosis-associated liver disease: Typically 20 mg/kg/day in 2-3 divided doses.

Side Effects: Common side effects may include diarrhea, nausea, vomiting, abdominal discomfort, and pruritus (itching). Less common side effects may include headache, dizziness, fatigue, and hair loss.

Precautions: Udihep is contraindicated in patients with:

• Non-visualizing gallbladder.
• Calcified gallstones.
• Gallbladder inflammation or biliary obstruction.
• Frequent episodes of biliary colic.
• Hypersensitivity to ursodeoxycholic acid.
• Severe liver disease.
• Inflammatory bowel disease.

Caution should be exercised in patients with liver impairment, and liver function tests may be monitored regularly. Women of childbearing potential should use effective non-hormonal contraception.

Use in Pregnancy and Lactation: Udihep should be used during pregnancy only if clearly needed and the potential benefits outweigh the risks. It is not known whether ursodeoxycholic acid is excreted in human milk; therefore, caution should be exercised in breastfeeding women.

Storage: Store below 25°C, protected from light and moisture. Keep out of reach of children.

Important Note: This information is for general knowledge and informational purposes only, and does not substitute professional medical advice. Always consult your doctor or pharmacist for specific instructions and guidance regarding your medication. They can assess your individual medical condition and provide the most appropriate advice.