Vasocor 5

Description

Vasocor 5 contains nebivolol. It is available in tablet form.

Indications

Vasocor 5 is indicated for:

• Treatment of essential hypertension.

• Adjunct in stable mild to moderate chronic heart failure in patients over 70 years.

Dosage & Administration

• Adults: The usual starting dose is 5 mg once daily. The maximum recommended dose is 40 mg once daily.

• Renal Impairment: In patients with severe renal impairment, the recommended initial dose is 2.5 mg once daily. The dosage may be titrated up slowly if needed.

• Hepatic Impairment: In patients with moderate hepatic impairment, the recommended initial dose is 2.5 mg once daily. The dosage may be titrated up slowly if needed.

Vasocor 5 can be taken with or without food.

Contraindications

Vasocor 5 is contraindicated in the following conditions:

• Severe bradycardia

• Heart block greater than first degree

• Cardiogenic shock

• Decompensated cardiac failure

• Sick sinus syndrome

• Patients with severe hepatic impairment

• Patients who are hypersensitive to any component of the product

Precautions & Warnings

• Caution should be exercised in patients with inadequate cardiac function.

• It should be used with caution in patients with well-compensated heart failure.

• Caution is advised in patients with myasthenia gravis.

• Patients undergoing major surgery involving general anesthesia should use it with caution.

• It may mask signs and symptoms of hypoglycemia and hyperthyroidism.

• Abrupt withdrawal may exacerbate angina symptoms and/or precipitate myocardial infarction and ventricular arrhythmias in patients with coronary artery disease.

• Use with caution during pregnancy and lactation.

Side Effects

The most common side effects are:

• Headache

• Nausea

• Bradycardia

Other side effects may include fatigue, dizziness, diarrhea, and constipation.

Drug Interactions

• Use caution when Vasocor 5 is co-administered with CYP2D6 inhibitors (e.g., quinidine, propafenone, fluoxetine, paroxetine).

• Do not use Vasocor 5 with other beta-blockers.

• Both digitalis glycosides and beta-blockers slow atrioventricular conduction and decrease heart rate. Concomitant use can increase the risk of bradycardia.

• Vasocor 5 can exacerbate the effects of myocardial depressants or inhibitors of AV conduction, such as certain calcium antagonists (verapamil and diltiazem) or antiarrhythmic agents (e.g., disopyramide).

Overdose

Symptoms of overdose may include bradycardia, hypotension, cardiac failure, dizziness, fatigue, hypoglycemia, vomiting, bronchospasm, and heart block.

Storage

Store between 20-25°C. Protect from light. Keep out of the reach of children.

Important Note: This information is for general knowledge and informational purposes only, and does not substitute professional medical advice. Always consult your doctor or pharmacist for specific instructions and guidance regarding your medication. They can assess your individual medical condition and provide the most appropriate advice.