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Presentation:Tablets containing vildagliptin 50 mg.
Indications:Indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus.May be used as monotherapy or in combination with other antidiabetic agents, including metformin, sulfonylureas, thiazolidinediones, and insulin.
Dosage and Administration:The usual recommended dose is 50 mg once or twice daily.When used in combination with a sulfonylurea, the recommended dose is 50 mg once daily in the morning.In combination with metformin, a thiazolidinedione, or insulin, the recommended dose is 50 mg twice daily, once in the morning and once in the evening. Dosage adjustment may be necessary in patients with moderate or severe renal impairment. It can be taken with or without food.Follow physician's instructions based on individual needs and renal function.
Side Effects:Vildagliptin is generally well-tolerated.Common side effects may include nasopharyngitis, headache, dizziness, and nausea. Hypoglycemia may occur when used in combination with insulin or sulfonylureas. Peripheral edema has been reported, particularly in combination with thiazolidinediones. Rarely, liver enzyme elevations have been observed.
Precautions: Use with caution in patients with moderate or severe renal impairment; dosage adjustment is recommended. Monitor liver function tests periodically. Not recommended for use in patients with severe hepatic impairment. Caution should be exercised in patients with a history of heart failure. Hypoglycemia risk is increased when used with insulin secretagogues (e.g., sulfonylureas).
Storage:Store below 30°C, in a dry place, protected from light and moisture.Keep out of reach of children.
Important Note: This information is for general knowledge only, not medical advice. Consult your doctor or pharmacist for specific guidance.
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