Xorel 20 mg Capsuleis a proton pump inhibitor (PPI) that suppresses gastric acid secretion.It is used to treat conditions such as duodenal ulcers, gastric ulcers, gastro-esophageal reflux disease (GERD), Zollinger-Ellison Syndrome, and to eradicate Helicobacter pylori.

Dosage:

• Active duodenal and benign gastric ulcers: 20 mg once daily, preferably in the morning.
• Erosive or ulcerative GERD: 20 mg once daily for 4-8 weeks.
• Long-term management of GERD: A maintenance dose of 20 mg or 10 mg once daily, depending on patient response.
• Symptomatic GERD without esophagitis:10 mg once daily.
• Zollinger-Ellison Syndrome: Starting dose is 60 mg once a day, which may be adjusted up to 120 mg/day.
• To eradicate H. pylori: A combination therapy including Rabeprazole sodium 20 mg twice daily, clarithromycin 500 mg twice daily, and amoxicillin 1g twice daily is recommended for 7 days.

Side Effects:

• Common side effects include diarrhea, constipation, nausea, vomiting, headache, dizziness, rash, and dry mouth.
• Serious side effects are rare but can include kidney problems, liver damage, and bone fractures.  
• Long-term use can cause thinning of bones (osteoporosis) and may lead to calcium deficiency.